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Dr Peter MacPherson

 Peter Macpherson 000

Peter's Clinical PhD Programme Experience:

"I had previously worked in rural South Africa and identified a high rate of drop-out among HIV-infected patients waiting to start ART treatment. I had previously done some research work and wanted to undertake studies to clearly define this problem, and identify and trial potential solutions. So far, I have had a considerable number of achievements, including running the first ever cluster randomised trial to investigate strategies to improve linkage to antiretroviral therapy. Additionally, I have gained substantial experience in presentation and publishing, having now had 15 peer-reviewed manuscripts describing primary research accepted for publication.

As I come to the end of my Fellowship, the key achievement had been presenting my cluster-randomised trial results at the biggest global academic HIV conference (CROI). These results showed for the first time, an effective strategy to improve linkage to ART. The results have stimulated considerable international interest and I gave a press conference to release the results.

After my Fellowship, I am going to commence higher specialty training in Public Health in the UK (Cheshire and Merseyside rotation). I plan to use this time to develop a proposal for an higher level fellowship."

Publications for Peter MacPherson

Publication Discordant Immune Response with Antiretroviral Therapy in HIV-1: A Systematic Review of Clinical Outcomes
Kelly C, Gaskell KM, Richardson M, Klein N, Garner P, MacPherson P

Publication Uptake, Accuracy, Safety, and Linkage into Care over Two Years of Promoting Annual Self-Testing for HIV in Blantyre, Malawi: A Community-Based Prospective Study.
Choko AT, MacPherson P, Webb EL, Ball, H, Sambakunsi R, Mdolo A, Makombe SD, Desmond N, Hayes RJ, Maheswaran H, Corbett EL

Publication Field accuracy of fourth-generation rapid diagnostic tests for acute HIV-1: a systematic review.
Lewis JM, Macpherson P, Adams ER, Ochodo E, Sands A, Taegtmeyer M.

Publication Should doctors record their patients’ income?
Andrew Moscrop, Peter MacPherson

Publication Diagnostic accuracy of the WHO clinical staging system for defining eligibility for ART in sub-Saharan Africa: a systematic review and meta-analysis.
Munthali C, Taegtmeyer M, Garner PG, Lalloo DG, Squire SB, Corbett EL, Ford N, MacPherson P

Publication Effect of optional home initiation of HIV care following HIV self-testing on antiretroviral therapy initiation among adults in Malawi: a randomized clinical trial.
MacPherson P, Lalloo DG, Webb EL, Maheswaran H, Choko AT, Makombe SD, Butterworth AE, van Oosterhout JJ, Desmond N, Thindwa D, Squire SB, Hayes RJ, Corbett EL.

Publication Pre-treatment loss to follow-up in tuberculosis patients in low- and lower-middle-income countries and high-burden countries: a systematic review and meta-analysis.
MacPherson P, Houben RM, Glynn JR, Corbett EL, Kranzer K3

Publication A novel community health worker tool outperforms WHO clinical staging for assessment of antiretroviral therapy eligibility in a resource-limited setting
Macpherson P, Lalloo DG, Thindwa D, Webb EL, Squire SB, Chipungu GA, Desmond N, Makombe SD, Taegtmeyer M, Choko AT, Corbett EL

Publication TB screening in high HIV prevalence settings: turning promise into reality
Corbett EL, MacPherson P

Publication Evidence of improving antiretroviral therapy treatment delays: an analysis of eight years of programmatic outcomes in Blantyre, Malawi
Derek J Sloan, Joep J van Oosterhout, Ken Malisita, Eddie M Phiri, David G Lalloo, Bernadette O’Hare, Peter MacPherson

Publication Development and Validation of a Global Positioning System-based "Map Book" System for Categorizing Cluster Residency Status of Community Members Living in High-Density Urban Slums in Blantyre, Malawi
Peter MacPherson, Augustine T. Choko, Emily L. Webb, Deus Thindwa, S. Bertel Squire, Rodrick Sambakunsi, Joep J. van Oosterhout, Treza Chunda, Kondwani Chavula, Simon D. Makombe, David G. Lalloo, Elizabeth L. Corbett

Publication Correlates of Delayed Diagnosis among Human Immunodeficiency Virus-Infected Pulmonary Tuberculosis Suspects in a Rural HIV Clinic, South Africa
Boniface R, Moshabela M, Zulliger R, MacPherson P, Nyasulu P.

Publication Clinical and social determinants of diarrhoeal disease in a rural HIV/AIDS clinic, South Africa: a case-control study
Moshabela M, MacPherson P, Ezard N, Frean E, Mashimbye L, Elliott JH, Oldenburg B.

Publication Barriers and facilitators to linkage to ART in primary care: a qualitative study of patients and providers in Blantyre.
Peter MacPherson, Eleanor E MacPherson, Daniel Mwale, Stephen Bertel Squire, Simon D Makombe, Elizabeth L Corbett, David G Lalloo, Nicola Desmond

Publication Determinants and consequences of failure of linkage to antiretroviral therapy at primary care level in Blantyre, Malawi: a prospective cohort study.
Peter MacPherson, Elizabeth L. Corbett, Simon D. Makombe, Joep J. van Oosterhout, Eddie Manda, Augustine T. Choko, Deus Thindwa, S. Bertel Squire, Gillian H. Mann, David G. Lalloo

Publication Suboptimal patterns of provider initiated HIV testing and counselling, antiretroviral therapy eligibility assessment and referral in primary health clinic attendees in Blantyre, Malawi.
MacPherson P, Lalloo DG, Choko AT, Mann GH, Squire SB, Mwale D, Manda E, Makombe SD, Desmond N, Heyderman R, Corbett EL.

Publication Risk factors for mortality in smear-negative TB suspects: a cohort study in Harare, Zimbabwe
MacPherson P, Dimairo M, Bandason T, Zezai A, Munyati S, Butterworth AE, Mungofa S, Rusakaniko S, Fielding K, Mason PR, Corbett EL.

Publication Feasibility and acceptability of point of care HIV testing in community outreach and GUM drop-in services in the North West of England: A programmatic evaluation
MacPherson P, Chawla A, Jones K, Coffey E, Spaine V, Harrison I, Jelliman P, Phillips-Howard P, Beynon C and Taegtmeyer M.

Publication Stigmatising Attitudes among People Offered Home-Based HIV Testing and Counselling in Blantyre, Malawi: Construction and Analysis of a Stigma Scale
MacPherson P, Webb EL, Choko AT, Desmond N, Chavula K, Napierala Mavedzenge S, Makombe SD, Chunda T, Squire SB, Corbett EL

Publication Programmatic evaluation of a combined antigen and antibody test for rapid HIV diagnosis in a community and sexual health clinic screening programme.
Miriam Taegtmeyer, Peter MacPherson, Kathy Jones, Mark Hopkins, Jay Moorcroft, David G. Lalloo, Anu Chawla

Publication The Risk and Timing of Tuberculosis Diagnosed in Smear-Negative TB Suspects: A 12 Month Cohort Study in Harare, Zimbabwe
Dimairo M, MacPherson P, Bandason T, Zezai A, Munyati SS, Butterworth AE, Mungofa S, Rusikaniko S, Fielding K, Mason PR, Corbett EL.


Young Investigator Award, 19th Conference on Retroviruses and Opportunistic Infections, Seattle, USA, 2012
Young Investigator Award, 18th Conference on Retroviruses and Opportunistic Infections, Boston, USA, 2010

Conferences & Presentations:

MacPherson P, Dimairo M, Bandason T, Zezai A, Munyati S, Mungofa S, Rusakaniko S, Fielding K, Mason P, Corbett EL. Risk Factors and Timing of Mortality in HIV-Positive Smear-Negative TB Suspects; a 12-Month Cohort Study in Harare, Zimbabwe. Poster, Conference on Retroviruses and Opportunistic Infections (CROI) 2011, Boston, USA, Feb 2011.
Moshabela M, MacPherson P, Ezard N, Frean E, Mashimbye L, Elliot J, Oldenburg B. Clinical and socio-environmental determinants of diarrhoeal disease in a rural South African HIV clinic: a case-control study. 6th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention, Rome, Italy, July 2011.
MacPherson P, Lalloo DG, Choko AT, van Oosterhout JJ, Thindwa D, Webb EL, Squire SB, Makombe SD, Hayes RJ, Corbett EL. Home Assessment and Initiation of ART Following HIV Self-Testing: a Cluster-Randomised Trial to Improve Linkage to ART in Blantyre, Malawi. 20th Conference on Retroviruses and Opportunistic Infections, Atlanta, USA. March 2013.
MacPherson P, Lalloo DG, Squire SB, Choko AT, Makombe SD, Desmond N, Thindwa, D, van Oosterhout JJ, Taegtmeyer M, Webb EL, Hayes RJ, Corbett EL.Home initiation of HIV care following self-testing to improve uptake of HIV care: a cluster randomised trial in Blantyre, Malawi. 2nd Annual HIV Treatment as Prevention (TaSP) Conference, London, UK. Sept 2013. (Abstract first prize awarded).
Munthali C, Taegtmeyer M, Garner PG, Lalloo DG, Corbett EL,MacPherson P. Accuracy of WHO clinical staging system for assessing eligibility of individuals for ART in sub-Saharan Africa: systematic review and meta-analysis. 2nd Annual HIV Treatment as Prevention (TaSP) Conference, London, UK. Sept 2013.
Mutetwa R,MacPherson P, Sagonda T, Manzou R, Makamure B, Mungofi S, Mupfumi L, Odland J, Mason P, Nicol M, Corbett EL. Preventing adverse outcomes in patients suspected with smear-negative TB: a randomised clinical trial of Xpert MTB/RIF testing in primary care clinics in Harare, Zimbabwe. 44th Union World Conference on Lung Health, Paris, France. Nov 2013.
MacPherson P. HIV self-testing: lessons from the field and future priorities. WHO/UNAIDS South East Asian regional meeting on community-based HIV testing: challenges and opportunities. Bangkok, Thailand. Oct 2013

Baggaley R, Corbett EL, Marum E, Davyduke T, Johnson C, Sigurdson J,MacPherson P, Ncube B, Taegtmeyer M. The legal, ethical, gender,human rights and public health implications of HIV self-testing scale-up: lessons learned and next steps from the first internationalsymposiumon self-testing for HIV. 17th International Conference on HIV/AIDS and STIs in Africa (ICASA). Cape Town, South Africa. December 2013.